Yes, of course you can. And, it would be best to wash it first (which I did). This sock is on the way to France for a mail art call. The theme is Past, Present & Tomorrow and the piece must include some textile element. Why an old sock? Well, I always like to recycle and re-use. Old socks get worn out (past) and full of holes (present) and can end up in the rag bag (tomorrow) to be used for dusting your knick-knacks, or in this example, cleaning unused ink off my rubber stamps.